COT I human DNA

The COT I human DNA is used as a blocking reagent for applications like:

  • in situ hybridizations,
  • microarrays,
  • filter hybridizations and
  • comparative genomic hybridization (CGH).

The COT I DNA is prepared from male humen placental DNA, exclusively. The COT I DNA fraction consists mainly of rapidly annealing repetitive elements. These interspersed repetitive sequences (IRS), such as SINEs (small interspersed repetitive elements, e.g., Alu elements) and LINEs (large interspersed repetitive elemnets, e.g., L1 elements), are distributed ubiquitously throughout the genome.


Concentration: > 1,1 mg/ml; Solution in 10 mM Tris-HCl, 1 mM EDTA, pH 7.4

Transport: on ice

Storage: at -20°C for more than 12 months


Sample request - please see below


Quality control:

- Average fragments size: 50-300 bp

- A260/A280 ration:  about 1.78

- Amount of genomic (non-repetitive) DNA: less than 2%

- COT I DNA and the raw material is tested for the absence of HIV1,2 RNA, HCV RNA, HBV DNA

0,00 €

  • verfügbar
  • 1 - 3 Tage Lieferzeit1

COT I human DNA
Cot I Human DNA_Biovendis.pdf
Adobe Acrobat Dokument 106.6 KB